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Access from Stats GUI (right)
Choose any combination of VOI and fMRI
For each fMRI and VOI:
Go to 1st level SPM
E.g.: …\fMRIpreprocess\…\SPMboxcar_s6wcrLinear\
Create a VOI subfolder
E.g.: …\fMRIpreprocess\…\SPMboxcar_s6wcrLinear\VOI\Hipp L\
Get F-contrast for All Effects (calculate if necessary)
Run Results with no threshold (P = 1 => F = 0) and VOI as mask
batch file: job_1stlevelVOIresults4ppi
Extract Eigenvariate using VOI as mask, no adjustment
Saves in VOI_…mat
Move to VOI folder
Create PPI variable (SPM PPI)
Saved in PPI_…mat in VOI folder
Create new SPM model with PPI variables as regressors
Saved in VOI folder
batch file: job_design_ppi
Estiamte model
Create T contrast of 1st variable (interaction)
con_0001.nii
Copy file to group folder for 2nd level analysis (prepend filename with study name)
CSPM will create a new fMRI measure than can be analysed with the SPM. (Need to re-load).
References:
Chapter 36 of SPM manual
Andy’s Brain Book “Psychophysiological Interactions (PPI) in SPM”