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  • native space - original MRI 
  • isotropic scaling - scaling that is the same in all directions

 MNI space is a standard space (an average of many individuals)
and native space is the space of the subject without adjusting it
to fit the average. The main difference is that if your subjects are
different from the "average" (e.g. older) then there can be a difference
between the MNI space and native space results (as the former will
scale each image to match the average/standard space). I would
recommend the MNI space analysis in general (as it adjusts for
head size). (link)

UseScale

  • Does rigid body registration
  • Resizes each volume to the other - accounts for structure size, not head size
    • Picks up differences in shape but not volume
  • 7 DOF - Rigid Align (6 DOF) + isotropic scaling (1 DOF)

Rigid Align

  • 6 DOF
  • Places the structures in the same place

 

MNI

  • Doesn't change the shape
  • Allows us to look at the volume based on the volume of head
  • Doesn't make sense to useScale and ReconMNI because MNI distorts the shape and then you're trying to look at the shape
doMVGLM

This option is used for the old-style vertex analysis. It is not needed in the new-style vertex analysis which uses randomise. (link)

 

Shape differences - ReconNative, RigidAlign, useScale

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