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R

R is a free statistical analysis package with extensive community support.

Link with Matlab

There is a File Exchange demonstration; see also the R manual, Chpt 7 Network interfaces, 7.3 DCOM interface. The DCOM connector is on the other-software part of the CRAN mirror; they have a web manual and very helpful WIKI.

Unequal variance t-test

Two-sample t-tests usually assume equal variance between the groups, which is only well-justified in a subset of instances. The unequal variance t-test can be performed in Matlab, SPSS, and should be the default for groups of differing subjects. ( Document Icon Here is a nice paper.)

Statistical thinking

A nice paper:

Rule 1: Statistical Methods Should Enable Data to Answer Scientific Questions

Rule 2: Signals Always Come with Noise

Rule 3: Plan Ahead, Really Ahead

Rule 4: Worry about Data Quality

Rule 5: Statistical Analysis Is More Than a Set of Computations

Rule 6: Keep it Simple

Rule 7: Provide Assessments of Variability

Rule 8: Check Your Assumptions

Rule 9: When Possible, Replicate!

Rule 10: Make Your Analysis Reproducible