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Re different MD values, in theory nothing should matter in terms of raw intensities, as explained below. However, if there is a consistent pattern of low MD having high absolute dw/b0 values, then it might point to an issue. For example, there might be so much dropout from the dw effect that the values have a floor effect. Alternatively, there might be an issue with susceptibility dropout.

Question - scaling?

I still cant work out why those mouse MD maps are so much lower in value.

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