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2023-11 AHA invited talk brain complexity

2023-11 AHA invited talk brain complexity

Notes from talk


Incorporate sleep into CV risk factors - 10 years - Nov 22, AHA

I am brain

https://newsroom.heart.org/news/american-heart-association-adds-sleep-to-cardiovascular-health-checklist#:~:text=Sleep%20duration%20(new)%3A%20Sleep,9%20hours%20daily%20for%20adults.

Sleep duration (new): Sleep duration is associated with cardiovascular health. Measured by average hours of sleep per night, the ideal level is 7-9 hours daily for adults. Ideal daily sleep ranges for children are 10-16 hours per 24 hours for ages 5 and younger; 9-12 hours for ages 6-12 years; and 8-10 hours for ages 13-18 years.

life's essential 8

Framework - insulin resistance, diabetes, obesity, (life's simple 7, sleep (pathophysiology)

  • insulin cardiometabolic syndrome framework

Biological basis - brain, heart: mechnisms include

  • endothelial function focus for Somers, manifestations as seen in the heart, in the brain

  • heart brain vascular beds, endothelial function implicated for simple 7
    => sefway to life essential 8

  • But what is common mechanisms across life's essential 8/insulmin metabolic syndromes?

CVLaim: know, strong eviodence, speculative

Vasolidator abnormality in HF, vessel problems

Expand simple 7 to essential 8 - how are integrated

Behavioral aspcet - managing

Tie essential 8 to insulin metabolic syndrome

Garth: oxygen delivery deficit

Fullness of funcitonal manifestations - visualize with imaging = power of seminar


Lit

Life’s essentioal 8

https://www.ahajournals.org/doi/epub/10.1161/CIR.0000000000001078

https://www.ahajournals.org/journal/circ

 

Graph theory - useless for brain

https://en.wikipedia.org/wiki/Graph_theory

 

Altered cortical structure network in children with obstructive sleep apnea NCBI - WWW Error Blocked Diagnostic

 

Pubmed - osa brain resting state fMRI NCBI - WWW Error Blocked Diagnostic