2023-11 AHA invited talk brain complexity
Notes from talk
Incorporate sleep into CV risk factors - 10 years - Nov 22, AHA
I am brain
Sleep duration (new): Sleep duration is associated with cardiovascular health. Measured by average hours of sleep per night, the ideal level is 7-9 hours daily for adults. Ideal daily sleep ranges for children are 10-16 hours per 24 hours for ages 5 and younger; 9-12 hours for ages 6-12 years; and 8-10 hours for ages 13-18 years.
life's essential 8
Framework - insulin resistance, diabetes, obesity, (life's simple 7, sleep (pathophysiology)
insulin cardiometabolic syndrome framework
Biological basis - brain, heart: mechnisms include
endothelial function focus for Somers, manifestations as seen in the heart, in the brain
heart brain vascular beds, endothelial function implicated for simple 7
=> sefway to life essential 8But what is common mechanisms across life's essential 8/insulmin metabolic syndromes?
CVLaim: know, strong eviodence, speculative
Vasolidator abnormality in HF, vessel problems
Expand simple 7 to essential 8 - how are integrated
Behavioral aspcet - managing
Tie essential 8 to insulin metabolic syndrome
Garth: oxygen delivery deficit
Fullness of funcitonal manifestations - visualize with imaging = power of seminar
Lit
Life’s essentioal 8
https://www.ahajournals.org/doi/epub/10.1161/CIR.0000000000001078
https://www.ahajournals.org/journal/circ
Graph theory - useless for brain
https://en.wikipedia.org/wiki/Graph_theory
Altered cortical structure network in children with obstructive sleep apnea NCBI - WWW Error Blocked Diagnostic
Pubmed - osa brain resting state fMRI NCBI - WWW Error Blocked Diagnostic