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From redifining stress concept

From redifining stress concept

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Huda Akil

SfN 2022 History of Neuroscience Lecture

Nov. 15, 2022

 

Neuroscience Redefines the Stress Concept:

From "Fight or Flight" to Neuroplasticity and Affective Disorders.

References Cited

(In Order of Appearance During Presentation)

 

  1.  

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*** Kindle Book by Walter Cannon: Bodily Changes in Pain, Hunger, Fear and Rage - An Account of Recent Researches Into the Function of Emotional Excitement (1927)

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14. Akil H, Mayer DJ, Liebeskind JC. Comparison chez le rat entre l'analgésie induite par stimulation de la substance grise péri-aqueducale et l'analgésie morphinique [Comparison in the rat between analgesia induced by stimulation of periacqueducal gray matter and morphine analgesia]. C R Acad Hebd Seances Acad Sci D. 1972 Jun 26;274(26):3603-5. French. PMID: 4265157.

15. Akil H, Mayer DJ, Liebeskind JC. Antagonism of stimulation-produced analgesia by naloxone, a narcotic antagonist. Science. 1976 Mar 5;191(4230):961-2. doi: 10.1126/science.1251210. PMID: 1251210.

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26. Watson SJ, Akil H, Richard CW 3rd, Barchas JD. Evidence for two separate opiate peptide neuronal systems. Nature. 1978 Sep 21;275(5677):226-8. doi: 10.1038/275226a0. PMID: 211426.

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30. Shiomi H, Watson SJ, Kelsey JE, Akil H. Pretranslational and posttranslational mechanisms for regulating beta-endorphin-adrenocorticotropin of the anterior pituitary lobe. Endocrinology. 1986 Oct;119(4):1793-9. doi: 10.1210/endo-119-4-1793. PMID: 3019643.

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39. Herman JP, Cullinan WE, Young EA, Akil H, Watson SJ. Selective forebrain fiber tract lesions implicate ventral hippocampal structures in tonic regulation of paraventricular nucleus corticotropin-releasing hormone (CRH) and arginine vasopressin (AVP) mRNA expression. Brain Res. 1992 Oct 2;592(1-2):228-38. doi: 10.1016/0006-8993(92)91680-d. PMID: 1333341.

40. Cullinan WE, Herman JP, Watson SJ. Ventral subicular interaction with the hypothalamic paraventricular nucleus: evidence for a relay in the bed nucleus of the stria terminalis. J Comp Neurol. 1993 Jun 1;332(1):1-20. doi: 10.1002/cne.903320102. PMID: 7685778.

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57. Birt IA, Hagenauer MH, Clinton SM, Aydin C, Blandino P Jr, Stead JDH, Hilde KL, Meng F, Thompson RC, Khalil H, Stefanov A, Maras P, Zhou Z, Hebda-Bauer EK, Goldman D, Watson SJ Jr, Akil H. Genetic Liability for Internalizing Versus Externalizing Behavior Manifests in the Developing and Adult Hippocampus: Insight From a Meta-analysis of Transcriptional Profiling Studies in a Selectively Bred Rat Model. Biol Psychiatry. 2021 Feb 15;89(4):339-355. doi: 10.1016/j.biopsych.2020.05.024. Epub 2020 May 27. PMID: 32762937; PMCID: PMC7704921.

58. Chitre, AS, Hebda-Bauer, EK et al . Genome-Wide Association Study in a Rat Model of Temperament Identifies Multiple Loci for Exploratory Locomotion and Anxiety-Like Traits. Frontiers in Genetics, 2022 In press.

59. Maras PM, Hebda-Bauer EK, Hagenauer MH, Hilde KL, Blandino P Jr, Watson SJ Jr, Akil H. Differences in microglia morphological profiles reflect divergent emotional temperaments: insights from a selective breeding model. Transl Psychiatry. 2022 Mar 15;12(1):105. doi: 10.1038/s41398-022-01821-4. PMID: 35292624; PMCID: PMC8924221.

60. Young EA, Haskett RF, Murphy-Weinberg V, Watson SJ, Akil H. Loss of glucocorticoid fast feedback in depression. Arch Gen Psychiatry. 1991 Aug;48(8):693-9. doi: 10.1001/archpsyc.1991.01810320017003. PMID: 1652926.

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62. Evans SJ, Choudary PV, Neal CR, Li JZ, Vawter MP, Tomita H, Lopez JF, Thompson RC, Meng F, Stead JD, Walsh DM, Myers RM, Bunney WE, Watson SJ, Jones EG, Akil H. Dysregulation of the fibroblast growth factor system in major depression. Proc Natl Acad Sci U S A. 2004 Oct 26;101(43):15506-11. doi: 10.1073/pnas.0406788101. Epub 2004 Oct 13. PMID: 15483108; PMCID: PMC523463.

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