2006 HF

Subject information

CON 116 - converted to OSA116 after home sleep study
CON 131 - had low SaO2 (and PSQI 11)
CON 155 - cyst in insular cortex
OSA 200 - had earlier polysomnography confirming OSA, but Edwin's study did no - a little odd.
CON 233 - could not make valsalva; questions about cognitive control; do not use as control
CON 275 - white matter lesion
CON 293 converted to OSA293 after sleep study
CON 298 - does not appear to be good control; borderline diabetic; taking ACE/ ARB; statin
CON 300 - subject was dropping O2 sat until 83%. May have OSA?
CON 301- do not use as control; did not meet inclusion criteria; taking anti-depressants
CON 304 - taking anti-anxiety drug
CON 306 - possible case of traumatic brain injury; do not use as control
HF 169 - T1 shows evidence of major infarct affecting left basal ganglia

Diabetes
CON 300
HF 220
HF 295

Hypertension
CON 102
CON 111
CON 118
CON 162

The following page lists subjects separated by variables we have in the database - anxiety, etc.

OSAHF2006 subject info - measured characteristics

fMRI

Cold pressor

Global BOLD Control
CON 179 - large global BOLD in cold pressor
HF 297 - large global BOLD to cold pressor and hand grip

Motion HF motion motion Control
CON 113 - sustained > 4 mm
CON 126 - 2 timepoints > 4 mm
CON 178 - 1 timepoint > 4 mm

Physiology
CON 141 – irregular heart rate peaks in hand grip and cold pressor
CON 156 – O2 signal is absent for 20s during the cold pressor
CON 157 – no O2 signal from 1870-1970 s
CON 174 – O2 signal ends just after cold pressor
CON 273 – heart rate frequently jumps abruptly to 110 bpm during the cold pressor

Hand Grip

Global BOLD global Control global HF
HF 297 - large global BOLD to cold pressor and hand grip

Motion motion control motion HF
Controls OK
HF OK (N = 15)

Physiology
CON 141 – irregular heart rate peaks in hand grip and cold pressor

Valsalva

Global BOLD
HF 170 - large global BOLD to Valsalva; signal drops to -10%, much more extreme than other subjects (motion?).

Motion
CON 111 - 6-10 mm z-direction motion

Physiology
CON 155 – O2 signal ends just after fourth Valsalva
HF 199 - heart rate is good only through the third Valsalva (it is unreadable for the fourth Valsalva). HR is good for the hand grip and cold pressor
HF 217 - heart rate for cold pressor is unreadable. heart rate is OK for all other challenges.
HF 165, HF 168, HF 217, HF 220, HF 222, HF 256, HF 257 sometimes have aberrant heart beats, but are otherwise OK for physiology. strange peak.bmp

OSAHF2006 - List of subjects with good physiology
OSAHF2006 - List of unusable subjects (based on physiology and/or fMRI)

fMRI Timing (Note that 1st scan is included in challenge)

Valsalva (218 scans)
36-on
45-off
74-on
83-off
112-on
121-off
150-on
159-off

Hand Grip (Right) (218 scans)
36-on
44-off
74-on
82-off
112-on
120-off
150-on
158-off

Cold Pressor, Foot (Right) (150 scans)
60-on
90-off

Scanner Upgrades

VB11 up to subject 163 (DTI has 975 images), then VB13 (DTI has 13 images).

T2